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FLASH GENE
Symbol TFF2 contributors: mct - updated : 02-02-2015
HGNC name trefoil factor 2
HGNC id 11756
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
constitutional     --over  
in gastritis ulceration and metaplasia
tumoral     --over  
in some digestive tumors (stomach, pancreas, biliary tract)
tumoral     --low  
in gastric cancer
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • TFF2 and probably also TFF3 are candidate biomarkers for nephrolithiasis and possibly other inflammatory conditions of the urinary tract
  • Therapy target
    ANIMAL & CELL MODELS