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FLASH GENE

Symbol

PFKFB2

contributors: mct - updated : 08-06-2021

HGNC name	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
HGNC id	8873

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   significantly higher in hepatocellular carcinoma than in the corresponding nontumor tissues constitutional     --over   in placentas from pregnancies with IUGR

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	biomarker for thyroid cancer exhibiting differences in the correlation coefficients between benign and malignant samples that indicate its discriminatory power
	PFKFB2 promoter methylation analysis has potential applicability to better stratify WDTC patients according to the recurrence risk
Therapy target

ANIMAL & CELL MODELS