Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | TACR1 | contributors: mct - updated : 22-10-2013 |
HGNC name | tachykinin receptor 1 |
HGNC id | 11526 |
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RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | widely |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cells |
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cell lineage |
cell lines |
fluid/secretion |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES |
STRUCTURE |
motifs/domains
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HOMOLOGY |
Homologene |
FAMILY | G protein coupled receptor superfamily |
CATEGORY | signaling hormone , receptor membrane G |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm | |
text | localized in lipid rafts, and activation of TACR1 stimulates translocation of PKC into lipid rafts, where it interacts with the receptor and causes its desensitization |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component | TACR1 forms physical complexes with SLC6A2 |
INTERACTION |
DNA |
RNA |
small molecule |
protein | |
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cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) |
Other morbid association(s) |
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Susceptibility |
Variant & Polymorphism | |
Candidate gene | |||||||||||||||||||||||||||||
Marker | |||||||||||||||||||||||||||||
Therapy target | |||||||||||||||||||||||||||||
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ANIMAL & CELL MODELS |