Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

PTPRA

contributors: mct - updated : 25-10-2016

HGNC name	protein tyrosine phosphatase, receptor type, A
HGNC id	9664

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional       loss of function facilitates abnormal myelination and pronouncedly increases the number of non-landed oligodendrocyte loops at shortened paranodes in the spinal cord

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	Ptpra(-/-) mice were protected from pulmonary fibrosis induced by adenoviral-mediated expression of active TGFbeta1
	PTPalpha(-/-) mice have more oligodendrocyte lineage cells in embryonic forebrain and delayed oligodendrocyte progenitor cells (OPCs) maturation