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FLASH GENE
Symbol ACADL contributors: - updated : 05-10-2006
HGNC name acyl-Coenzyme A dehydrogenase, long chain
HGNC id 88
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
mono polymer homomer , tetramer
isoforms Precursor
HOMOLOGY
Homologene
FAMILY
CATEGORY enzyme
SUBCELLULAR LOCALIZATION     intracellular
intracellular,cytoplasm,organelle,mitochondria,matrix
basic FUNCTION
  • acyl-CoA dehydrogenase, long chain (C10-C18), unsaturated fatty acids, first step in the beta oxidation process
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism energetic , lipid/lipoprotein
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule cofactor, nucleotide,
    FAD+
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) ACADL
    related resource MITOP database
    Susceptibility susceptibility to autism
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
    ACADL deficiency increasing death rate in imbryo at the morula to blastocyst conversion