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FLASH GENE

Symbol

CRABP1

contributors: mct/npt - updated : 19-05-2010

HGNC name	cellular retinoic acid binding protein 1
HGNC id	2338

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral         renal cell carcinoma tumoral     --low   hypermethylation associated with low expression in papillary thyroid carcinoma and in colorectal tumor development tumoral     --over   contributing to retinoid resistance, in RARA-ZBTB16 acute myeloid leukemia phenotype tumoral     --low   by methylation-associated silencing in esophageal squamous-cell carcinoma (Tanaka 2007)

Susceptibility

Variant & Polymorphism

Candidate gene	elevated level of CRABPI in the CSF of patients with Moyamoçya disease
Marker
Therapy target

ANIMAL & CELL MODELS