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FLASH GENE
Symbol MMP9 contributors: mct/pgu - updated : 24-04-2019
HGNC name matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
HGNC id 7176
ANIMAL & CELL MODELS
  • key regulator of grow plate angiogenesis and apoptosis of hypertrophic chondrocytes in mice
  • Deletion of Mmp9 gene in mdx mice improved skeletal muscle structure and functions and reduced muscle injury, inflammation and fiber necrosis
  • Mmp9 deficiency causes physiological and placental abnormalities in mice, which mimic features of preeclampsia (PE)