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FLASH GENE
Symbol ALPPL2 contributors: - updated : 22-11-2005
HGNC name alkaline phosphatase, placental-like 2
HGNC id 441
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • one active site,
  • two zinc Zn2+ molecules, and magnesium Mg2+ as a cofactor
    • conjugated MetalloP
    mono polymer homomer , dimer
    HOMOLOGY
    intraspecies paralog to ACPP,ALPL
    Homologene
    FAMILY alkaline phosphatase family
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     plasma membrane
    text attached to the membrane by a gpi-anchor
    basic FUNCTION unknown
    CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component complex of identical subunits
    INTERACTION
    DNA
    RNA
    small molecule metal binding,
  • zinc Zn2+ binding
  • magnesium Mg2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --other  
    aberrantly expressed in seminoma
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS