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FLASH GENE
Symbol L1TD1 contributors: mct - updated : 25-05-2020
HGNC name LINE1 type transposase domain containing 1
HGNC id 25595
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
in non-small cell lung cancer (NSCLC)
tumoral     --over  
occurs in medulloblastoma cells, reaching levels similar to those found in ESCs, and is correlated with poor prognosis
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
  • increased expression of L1TD1 as a prognostic marker predicting longer disease-free survival in colon cancer patients
  • Therapy target
    SystemTypeDisorderPubmed
    cancerbrain 
    L1TD1 as a potential therapeutic target in malignant brain tumors
    ANIMAL & CELL MODELS