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FLASH GENE

Symbol

YTHDF3

contributors: mct - updated : 06-11-2019

HGNC name	YTH N6-methyladenosine RNA binding protein 3
HGNC id	26465

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   of YTHDF1, YTHDF3 and KIAA1429 predicted poor prognosis in terms of overall survival (OS) in breast cancer (BRC) tumoral       loss of function METTL14, YTHDF3 and ALKBH5 were downregulated in Colorectal cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	upregulation of YTHDF3 was an independent prognostic factor for overall survival (OS) in patients with breast cancer (BRC)
Therapy target

ANIMAL & CELL MODELS