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FLASH GENE

Symbol

TTC9

contributors: mct - updated : 21-09-2016

HGNC name	tetratricopeptide repeat domain 9
HGNC id	20267

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in breast cancer constitutional     --low   mammary TTC9A expression is distinctively down-regulated in gland undergoing functional differentiation (lactation) constitutional     --over   mammary TTC9A expression is up-regulated during involution of gland

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Ttc9a deficiency is associated with greater body weight, bigger thymus and better mammary development in post-pubertal mice