Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol TFAP2E contributors: mct - updated : 18-11-2013
HGNC name transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
HGNC id 30774
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY transcription factor
SUBCELLULAR LOCALIZATION     intracellular
intracellular,nucleus
text
  • expressed during late chondrocyte differentiation, especially in hypertrophic chondrocyte
    • basic FUNCTION
  • required for olfactory bulb development, specifically the establishment of appropriate neuronal lamination
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • promoter of the type II collagen (COL2A1) gene, is specifically regulated by TFAP2E
    • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • AP-2epsilon null mice were viable and could discriminate a variety of odors