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FLASH GENE

Symbol

TFAP2E

contributors: mct - updated : 18-11-2013

HGNC name	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)
HGNC id	30774

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	21.96 kb     7 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_178548 7 - 2189 NP_848643 - 442 - 2003 14636996

EXPRESSION

Type

expressed in	(based on citations)
organ(s)

cells

System Cell Pubmed Species Stage Rna symbol not specific chondrocyte Homo sapiens

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus
text	expressed during late chondrocyte differentiation, especially in hypertrophic chondrocyte

basic FUNCTION

required for olfactory bulb development, specifically the establishment of appropriate neuronal lamination

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

promoter of the type II collagen (COL2A1) gene, is specifically regulated by TFAP2E

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

AP-2epsilon null mice were viable and could discriminate a variety of odors