Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

VPS37A

contributors: shn - updated : 14-11-2015

HGNC name	vacuolar protein sorting 37 homolog A (S. cerevisiae)
HGNC id	24928

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SPG53

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	low HCRP1 expression was found to be of adverse prognostic significance in patients with oral and oropharyngeal squamous cell carcinoma
Therapy target

ANIMAL & CELL MODELS

	overexpression of HCRP1 (Vps37A) significantly inhibited both anchorage-dependent and anchorage-independent cell growth in vitro
	knock down of the expression of HCRP1 gene by shRNA in hepatocellular carcinoma cell line BEL-7404 result in the cell growth greatly enhanced
	Vps37A morpholino-injected zebrafish showed striking and significant loss of motility