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FLASH GENE
Symbol VGLL4 contributors: mct - updated : 06-01-2021
HGNC name vestigial like 4 (Drosophila)
HGNC id 28966
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --low  
was very important in the progression of esophageal squamous cell carcinoma (ESCC)
tumoral     --over  
reduces breast cancer cell proliferation, migration, intravasation/extravasation potential, favors cell death, and suppresses tumor growth
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerdigestiveoesophagus
restoring the function of VGLL4 might be a promising therapeutic strategy for ESCC
cancerreproductivebreast
may be a promising therapeutic target in breast cancer
ANIMAL & CELL MODELS