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FLASH GENE

Symbol

GRK4

contributors: mct/npt - updated : 10-11-2014

HGNC name	G protein-coupled receptor kinase 4
HGNC id	4543

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to essential hypertension

Variant & Polymorphism other	variant in isoform GRK4 gamma associated with essential hypertension
	65L allele is associated with stress-induced urinary sodium excretion reduction, suggesting impaired sodium handling in black normotensive adolescents

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS