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FLASH GENE
Symbol APEH contributors: - updated : 21-03-2005
HGNC name N-acylaminoacyl-peptide hydrolase
HGNC id 586
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
blood / hematopoieticthymus    
Cardiovascularheart    
Digestiveliver    
Endocrinepancreas    
Nervousbrain    
Reproductivemale systemprostate   
Respiratorylung    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Epithelialsecretoryglandularendocrine 
Epithelialsecretoryglandularexocrine 
Lymphoid    
Muscularstriatumskeletal  
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
conjugated Other
mono polymer homomer , tetramer
HOMOLOGY
interspecies homolog to murine Apeh
homolog to C.elegans R11E3.8
intraspecies homolog to the tightly linked MST1 gene highly
Homologene
FAMILY peptidase family S9C or prolyl oligopeptidase family
CATEGORY enzyme
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • serine protease
  • playing a role in destroying oxidatively damaged protein in living cells
    • CELLULAR PROCESS protein, degradation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component homotetramer of 300 kDa
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS