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FLASH GENE
Symbol PLD5 contributors: mct - updated : 16-03-2011
HGNC name phospholipase D family, member 5
HGNC id
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY signaling
SUBCELLULAR LOCALIZATION     plasma membrane
basic FUNCTION
  • its activity plays an important role in promoting IgE-dependent signaling events within lipid microdomains in mast cells
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to autism spectrum disorders
    Variant & Polymorphism SNP rs2196826 associated with autism spectrum disorders
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS