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FLASH GENE
Symbol IL17REL contributors: mct/npt - updated : 03-06-2010
HGNC name interleukin 17 receptor E-like
HGNC id 33808
EXPRESSION
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
CATEGORY unknown/unspecified
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • likely, oligomerizes and binds specific IL17 cytokines (Franke 2010)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility to ulcerative colitis
    Variant & Polymorphism SNP rs5771069 strongly associated with ulcerative colitis (Franke 2010)
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS