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FLASH GENE

Symbol

IL17REL

contributors: mct/npt - updated : 03-06-2010

HGNC name	interleukin 17 receptor E-like
HGNC id	33808

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	18.11 kb     15 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_001001694 15 - 3635 NP_001001694 - 336 - Albrecht (2010)

EXPRESSION

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION

basic FUNCTION

likely, oligomerizes and binds specific IL17 cytokines (Franke 2010)

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to ulcerative colitis

Variant & Polymorphism SNP	rs5771069 strongly associated with ulcerative colitis (Franke 2010)

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS