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FLASH GENE
Symbol IFNGR2 contributors: mct - updated : 11-07-2015
HGNC name interferon gamma receptor 2 (interferon gamma transducer 1)
HGNC id 5440
ASSOCIATED DISORDERS
corresponding disease(s) IFNGR2D
Susceptibility
  • to liver fibrosis in patients with chronic hepatitis C infection
  • to tuberculosis (TB)
  • Variant & Polymorphism SNP
  • two SNPs in strong linkage disequilibrium (LD) in IFNGR2 were significantly associated with liver fibrosis in patients with chronic hepatitis C infection
  • polymorphisms of IFNGR2 may confer resistance to the TB development of newly infected individuals
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS