| basic FUNCTION
| maintenance of the adult nervous system, development of neurons in embryo |
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playing an essential role for nervous system development |
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functional interchangeability between the pro-peptides of NGF and NTF3 with respect to their role in assisting oxidative folding of the mature part  |
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NTF3 and BDNF exert a profound effect on the types of neurotransmitter receptors expressed on postnatal spiral ganglion neurons, results that may have important implications for neural development and plasticity |
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has a role in the developmental mechanism that eliminates redundant synapses though it cannot modulate synaptic transmission locally as the NMJ matures |
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proNTF3 and proBDNF may play important roles in the response to noise-induced injuries or ototoxic damage via the Sortilin:NGFR death-signalling complex |
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has a distinctive role, not mimicked by BDNF, in promoting spiral ganglion neurons axon growth in the organ of Corti and synaptogenesis on inner hair cells |
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NGF and NTF3 collaborate to support development of sympathetic neurons, and NGF but not NTF3 supports retrograde survival of sympathetic neurons |
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motoneuron is a functional source of NTF3 and motoneuron-derived NTF3 is an essential pre-target neurotrophin for survival and axonal projection of sensory neurons |
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NTF3 can synergize with IGFBP2 to promote hematopoietic cell expansion |
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promoted differentiation of neural stem cells (NSCs) into cholinergic neurons and enhanced neuronal cell survival |
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role for gastrointestinal (GI) NTF3 in short-term controls of feeding, most likely involving effects on development of vagal GI afferents that regulate satiation |
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displays a non-canonical cell guidance signaling function for cephalic neural crest cells |
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in the cochlar nucleus, NTF3 had a strong impact on enhancement of neuronal survival, whereas BDNF stimulated neuronal survival and axonal outgrowth |
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NTF3 and BDNF are critical for sensory neuron survival and establishment of neuronal projections to sensory epithelia in the embryonic inner ear |
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regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma |
