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FLASH GENE

Symbol

IDUA

contributors: mct - updated : 14-11-2012

HGNC name	iduronidase, alpha-L-
HGNC id	5391

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

MPS1

related resource

Mucopolysaccharidosis

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

substantial elevation in heparan sulfate (HS) within the liver and brain of Idua -/- mice and significant changes in HS localization and sulfation patterning with significant increases in N-, 6-O-, and 2-O-sulfation