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FLASH GENE
Symbol KCNJ18 contributors: mct/npt - updated : 02-02-2010
DNA
TYPE functioning gene
STRUCTURE      3 Exon(s)
regulatory sequence Promoter
text structure thyroid hormone response cis element (TRE) within its promoter, which might drive increased expression of KCNJ18 to protect against membrane potential instability (Ryan 2010)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscularstriatumskeletal predominantly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
intraspecies paralog to KCNJ12
Homologene
FAMILY
  • inward rectifier-type potassium channel family
  • potassium channel subfamily J
    • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • inward rectifier potassium channel activity
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    Other regulated by thyroid hormone (Ryan 2010)
    ASSOCIATED DISORDERS
    corresponding disease(s) THYPOKPP2
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS