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FLASH GENE

Symbol

RASSF10

contributors: mct/npt/pgu - updated : 17-11-2009

HGNC name	Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
HGNC id	33984

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by frequent methylation of the associated 5prime-CpG island in acute lymphoblastic leukemia tumoral     --low   CpG island promoter was intensively methylated in nine thyroid cancer cell lines and in primary thyroid carcinomas

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	can potentially be developed into a prognostic marker for secondary glioblastomas
Therapy target

ANIMAL & CELL MODELS