Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

UCHL1

contributors: mct/npt/pgu - updated : 11-04-2018

HGNC name	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
HGNC id	12513

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	gracile axonal dystrophic mouse (gad) which arbors a deletion of Uchl1
	pharmacological inhibition of Uchl1 exacerbates rather than ameliorates disease symptoms in a mouse model of SMA
	Uchl1 knockout mice should serve as a useful model of gut aging