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FLASH GENE

Symbol

APRG1

contributors: SGE/npt - updated : 03-12-2009

HGNC name	chromosome 3 open reading frame 35
HGNC id	24082

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in breast cancer (expression negatively correlated with progressive disease: alive with metastasis, local recurrence, died of breast cancer, all progressive disease) tumoral     --low   frequently and extensively methylated in renal carcinoma cell lines tumoral   deletion     in renal, lung and breast carcinomas

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS