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FLASH GENE

Symbol

GIN1

contributors: mct - updated : 20-01-2009

HGNC name	gypsy retrotransposon integrase 1
HGNC id	25959

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_017676 8 - 3549 NP_060146 59.71 522 - 2001 11470852

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine large intestine colon     Homo sapiens   stomach         Homo sapiens Endocrine parathyroid       highly Homo sapiens Nervous brain         Homo sapiens Urinary kidney         Homo sapiens

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Muscular striatum cardiac     Homo sapiens Nervous central

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

pregnancy

Text

placenta

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

characteristic H2C2, DDE, and GPY/F motifs found in many retroviral and retrotransposon integrases

HOMOLOGY

interspecies

ortholog to murine Gin1 (85 p100)

Homologene

FAMILY

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION

basic FUNCTION

may be part of an analogous defense system, perhaps having contributed to the virtual absence of Ty3/Gypsy elements in mammalian genomes

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS