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FLASH GENE
Symbol FIZ1 contributors: mct/npt - updated : 12/12/2008
HGNC name FLT3-interacting zinc finger 1
HGNC id 25917
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • zinc finger protein family
    • CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may be a part of an interface between cell-specific factors, like NRL, and more ubiquitous regulatory networks that vary the absolute expression levels of some rod-specific genes (i.e. Rhodopsin)
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • synergized with NRL to activate transcription from the Rho and PDE6B gene promoters with some differences
    • cell & other
    REGULATION
    repressed by CRX, alone or with NRL, CRX decreased the synergy of NRL with FIZ1
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS