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FLASH GENE

Symbol

GJA3

contributors: mct/npt/shn - updated : 04-06-2012

HGNC name	gap junction protein, alpha 3, 46kDa
HGNC id	4277

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	mice homozygous for the disrupted alpha3 gene developed nuclear cataracts that were associated with the proteolysis of crystallins (
	Targeted null mutations in Gja3 in mice cause cataracts with recessive inheritance (
	double mutant offspring between Lop10 and the Gja3(tm1) (alpha 3(-/-)) mice showed relatively normal lens cortical fibers (