| basic FUNCTION
| with ANO9, can suppress baseline Cl- conductance when co-expressed with ANO1  |
|
specific function in the adult mature brain and especially in the cerebral cortex and the cerebellum, rather than in brain development |
|
involved in a variety of functions that include ion transport, phospholipid scrambling, and regulation of other membrane proteins |
|
is likely essential for Ca(2+)-dependent Cl(-) secretion in jejunum |
|
has a central role in innate immune defense against Borrelia infection |
|
modulates Ca2+ signals in macrophages and has a role in cerebellar ataxia and other neurological disorders |
|
ANO1 is responsible for basolateral Ca2+-dependent Cl- secretion in RPE, whereas ANO6 and ANO10 may have different functions, such as modulating Ca2+ signals |
