basic FUNCTION
| with ANO9, can suppress baseline Cl- conductance when co-expressed with ANO1  |
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specific function in the adult mature brain and especially in the cerebral cortex and the cerebellum, rather than in brain development  |
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involved in a variety of functions that include ion transport, phospholipid scrambling, and regulation of other membrane proteins  |
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is likely essential for Ca(2+)-dependent Cl(-) secretion in jejunum  |
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has a central role in innate immune defense against Borrelia infection  |
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modulates Ca2+ signals in macrophages and has a role in cerebellar ataxia and other neurological disorders  |
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ANO1 is responsible for basolateral Ca2+-dependent Cl- secretion in RPE, whereas ANO6 and ANO10 may have different functions, such as modulating Ca2+ signals  |