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FLASH GENE

Symbol

C9orf116

contributors: mct - updated : 28/10/2008

HGNC name	chromosome 9 open reading frame 116
HGNC id	28435

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	4.74 kb     3 Exon(s)

regulatory sequence	Promoter
text structure	strongly activated by TP53 via 2 cis-elements

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 - - 731 15.1 136 - - variant 2 - - 685 10.2 92 - -

EXPRESSION

Type

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive pharynx         Reproductive male system testis       Urinary kidney       highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

DNA associated

SUBCELLULAR LOCALIZATION

basic FUNCTION

an important TP53 target gene contributing to normal DNA damage response and may play crucial roles in maintaining genomic integrity against genotoxic stresses, including UVC irradiation

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	TP53 target gene contributing to the ultraviolet-induced DNA damage response

cell & other

REGULATION

induced by

genotoxic stresses that activate TP53

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS