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FLASH GENE
Symbol DRGX contributors: mct/ npt - updated : 22/10/2008
HGNC name dorsal root ganglia homeobox
HGNC id 21536
EXPRESSION
Type restricted
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Nervousgangliasensory gangliadorsal root  
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period embryo
Text in embryonic dorsal root ganglion (DRG) and dorsal horn neurons
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
  • paired homeobox family
    • CATEGORY transcription factor
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • may function in the establishment or maintenance of connectivity between some of these neurons and their central nervous system targets
  • playing a role in early postnatal survival of normally generated small primary afferent neurons innervating various kinds of peripheral tissues
  • paired domain transcription factor that is necessary for the assembly of the nociceptive circuitry in the spinal cord dorsal horn
  • required for the establishment of the first neuronal sensory relay along development
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS