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FLASH GENE

Symbol

DRGX

contributors: mct/ npt - updated : 22/10/2008

HGNC name	dorsal root ganglia homeobox
HGNC id	21536

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed DRGX 6 - 807 - 268 - Saito (1995)

EXPRESSION

Type	restricted

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Nervous ganglia sensory ganglia dorsal root

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

embryo

Text	in embryonic dorsal root ganglion (DRG) and dorsal horn neurons

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

HOMOLOGY

Homologene

FAMILY

paired homeobox family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION	may function in the establishment or maintenance of connectivity between some of these neurons and their central nervous system targets
	playing a role in early postnatal survival of normally generated small primary afferent neurons innervating various kinds of peripheral tissues
	paired domain transcription factor that is necessary for the assembly of the nociceptive circuitry in the spinal cord dorsal horn
	required for the establishment of the first neuronal sensory relay along development

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS