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FLASH GENE

Symbol

DBX2

contributors: KTN/npt - updated : 13/11/2008

HGNC name	developing brain homeobox 2
HGNC id	33186

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	36.34 kb     4 Exon(s)

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed DBX2 4 - 2722 36.4 339 - Pierani (2001)

EXPRESSION

Type

expressed in	(based on citations)
organ(s)

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective bone     lowly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

an homeobox DNA-binding domain

HOMOLOGY

interspecies	homolog to chimpanzee DBX2 (98.8 pc)
	homolog to cow DBX2 (86.1 pc)
	homolog to rattus Dbx2 (77.4 pc)
	homolog to murine Dbx2 (76.8 pc)
	homolog to chicken DBX2 (78.7 pc)

Homologene

FAMILY

H2.0 homeobox family

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus

basic FUNCTION

involved in DNA-dependent regulation of transcription

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA	binding to specific sequence

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS