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FLASH GENE

Symbol

MEIOB

contributors: mct - updated : 13-04-2021

HGNC name	meiosis-specific with OB domain-containing protein
HGNC id	28569

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

SPGF22

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional germinal mutation       a truncating MEIOB mutation responsible for familial primary ovarian insufficiency abolishes its interaction with its partner SPATA22

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Meiob-null mouse mutants exhibit a failure in meiosis and sterility in both sexes