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FLASH GENE

Symbol

INPP1

contributors: mct - updated : 27-05-2008

HGNC name	inositol polyphosphate-1-phosphatase
HGNC id	6071

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 1 6 - 1682 - 399 - Bremer (2007)

EXPRESSION

Type

widely

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine pancreas         Reproductive male system testis     highly Respiratory respiratory tract larynx     highly Urinary kidney       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Epithelial secretory glandular endocrine   Epithelial secretory glandular exocrine

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

Homologene

FAMILY

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION

basic FUNCTION	playing a possible role in lithium-treated bipolar illness
	involved in response to lithium prophylaxis in bipolar disorder

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to variability in response to lithium in bipolar disorder

Variant & Polymorphism other	variant modifying response to lithium prophylaxis in bipolar disorder

Candidate gene
Marker
Therapy target	targets for the therapeutic action of lithium in manic-depressive illness

ANIMAL & CELL MODELS