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FLASH GENE
Symbol SLC3A1 contributors: mct/npt - updated : 21-10-2009
HGNC name solute carrier family 3 (cystine, dibasic and neutral amino acid transporters, activator of cystine, dibasic and neutral amino acid transport), member 1
HGNC id 11025
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • six potential N-glycosylation sites which might be functional in the oocyte (Bertran 1993)
    • conjugated GlycoP
    mono polymer heteromer , dimer
    HOMOLOGY
    Homologene
    FAMILY
  • solute carrier family 3, neutral aminoacid
    • CATEGORY transport carrier
    SUBCELLULAR LOCALIZATION     plasma membrane
    text colocated in the brush border of the plasma membrane
    basic FUNCTION
  • Na+ dependent dibasic (cystine,lysine),neutral aminoacid transport,high affinity
  • mediating high affinity y+L-type transporter exchanging cationic aminoacids and/or neutral aminoacids
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • heterodimerizing with BO+AT (SLC3A1)
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) CSNU1 , HCYS
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS