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FLASH GENE
Symbol NPY1R last update : 24-06-2005
HGNC name neuropeptide Y receptor Y1
HGNC id 7956
Location 4q32.1-q32.2
Synonym symbol(s) NPYR1
DNA RNA EXP/sub-loc PROTEIN PATHOLOGY
DNA
TYPE functioning gene
SPECIAL FEATURE
text overlapping NPY5R,in opposite orientation
STRUCTURE 8.00 kb     3 Exon(s)
10 Kb 5' upstream gene genomic sequence study
MAPPING cloned Y linked   status confirmed
Physical map
LOC92345 4q32.2 hypothetical protein BC008207 LOC133332 4q32.2 mitochondrial ribosomal protein S5 pseudogene NPY1R 4q31.3-q32 neuropeptide Y receptor Y1 NPY5R 4q31-q32 neuropeptide Y receptor Y5 DKFZP434L1717 4q32.2 hypothetical protein DKFZp434L1717 FLJ11184 4q32.2 hypothetical protein FLJ11184 FLJ20668 4q32.2 hypothetical protein FLJ20668 ANP32C 4q32.2 acidic (leucine-rich) nuclear phosphoprotein 32 family, member C LOC389239 4 similar to ring finger protein 129 LOC391709 4 similar to 60S ribosomal protein L26 LOC391710 4 similar to ring finger protein 129 LOC389240 4 similar to alpha NAC/1.9.2. protein LOC391711 4 similar to ring finger protein 129 FLJ31659 4q32.3 hypothetical protein FLJ31659 LOC391712 4 similar to ring finger protein 129 LOC391713 4 similar to ring finger protein 129 RNF129 4q32.3 ring finger protein 129
RNA
TRANSCRIPTS type messenger
EXPRESSION / SUBCELLULAR LOCALIZATION
EXPRESSION (based on citations)
constitutive of
   expressed in
organ(s)
SystemOrgan 1organ 2organ 3organ 4level
Digestiveintestine    
Nervousbrainforebraincerebral cortex  
 brainbasal nucleistriatum  
Urinarykidney    
tissue
SystemTissueS_TissueSs_Tissuelevel
Epithelialabsorptive excretorydigestive epithelium  
Epithelialbarrier/lininguroepithelium  
Epithelialbarrier/lining   
Epithelialsecretoryglandularexocrine 
Nervouscentral   
cell lineage
cell lines
fluid/secretion
at STAGE
SUBCELLULAR LOCALIZATION     plasma membrane
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
seven transmembrane segments (7TM) receptor
HOMOLOGY
interspecies
 
intraspecies
 
Homologene
FAMILY G protein coupled receptor superfamily,rhodopsin-like
CATEGORY immunity/defense , receptor membrane G
basic FUNCTION neuropeptide Y receptor Y1
implicated in a
process
cellular process
physiological behavioral , nervous system
text
  • feeding behavior
  • electrogenic ion transport
  • pathway
    metabolism
    signaling signal transduction
    text isolated tumor colon
    a component
    structural
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • binding neuropeptide Y (NPY) and peptide YY (PYY), pancreatic polypeptide (PP°
  • receptor for PRLH
  • cell & other
    REGULATION
    other inducing the expression of CRE containing target genes through the CaM kinase-CREB pathway and inhibiting CRE containing genes when cellular cAMP is elevated
    ASSOCIATED DISORDERS