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FLASH GENE

Symbol

ACSF2

contributors: KTN/npt - updated : 25-06-2008

HGNC name	acyl-CoA synthetase family member 2
HGNC id	26101

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	48.00 kb     16 Exon(s)

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed ACSF2 16 - 2257 68 615 - -

EXPRESSION

Type

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Endocrine adrenal gland       predominantly Lymphoid/Immune thymus       moderately Urinary bladder       moderately   kidney       highly

tissue

System Tissue Tissue level 1 Tissue level 2 Level Pubmed Species Stage Rna symbol Connective adipose     moderately

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

HOMOLOGY

interspecies

homolog to murine Acsf2 (78.5 pc)

Homologene

FAMILY

ATP-dependent AMP-binding enzyme family

CATEGORY

enzyme

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria

basic FUNCTION	catalyzing the initial reaction in fatty acid metabolism, by forming a thioester with CoA
	playing a role in adipodyte differentiation
	having ligase activity

CELLULAR PROCESS	cell life, differentiation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

lipid/lipoprotein

signaling

fatty acid metabolism

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

induced by

PPARG

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS