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FLASH GENE
Symbol FAM134B contributors: mct/npt - updated : 30-05-2009
HGNC name family with sequence similarity 134, member B
HGNC id 25964
Corresponding disease
HSAN2B hereditary sensory and autonomic neuropathy type IIB
Location 5p15.1      Physical location : 16.473.147 - 16.617.118
Synonym name hypothetical protein LOC54463
Synonym symbol(s) FLJ20152, FLJ22155 , FLJ22179
DNA
TYPE functioning gene
STRUCTURE 143.97 kb     9 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
9 - 3259 54 497 - Tang (2007)
7 - 3108 - 356 - Tang (2007)
EXPRESSION
Type
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Endocrineparathyroid   highly
Nervousnerve    
Urinarykidney    
tissue
SystemTissueTissue level 1Tissue level 2LevelPubmedSpeciesStageRna symbol
Muscular    
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • FAM134 family
  • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION
    basic FUNCTION
  • has a prominent capacity to transform normal cells and may play a critical role in the molecular pathogenesis of esophageal squamous cell carcinoma (Tang 2007)
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) HSAN2B
    Other morbid association(s)
    TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
    tumoral     --over  
    in esophageal squamous cell carcinoma (Tang 2007)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS