Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

LTBP1

contributors: mct - updated : 23-06-2021

HGNC name	latent transforming growth factor beta binding protein 1
HGNC id	6714

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

CLCDSF

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in association with TGFB1 in ovarian cancer

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	mice lacking Ltbp1L only or both Ltbp1S and Ltbp1L show a persistent truncus arteriosus and an interrupted aortic arch that associates with perinatal lethality
	ltbp1 deficiency in zebrafish confirms a prominent role for Ltbp1 in skeletal morphogenesis