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FLASH GENE

Symbol

FAM83H

contributors: mct/npt - updated : 18-01-2023

HGNC name	family with sequence similarity 83, member H
HGNC id	24797

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

AIH4

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in liver cancer cells, and nuclear expression of FAM83H predicted shorter survival of HCC patients tumoral     --over   keratin filament disassembly caused by overexpression of FAM83H and aberrant localization of CSNK1A1 could contribute to the progression of colorectal cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	FAM83H expression as a poor prognostic indicator of hepatocellular carcinoma (HCC) patients
Therapy target

ANIMAL & CELL MODELS