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FLASH GENE
Symbol VASH2 contributors: mct - updated : 28-03-2008
HGNC name vasohibin 2
HGNC id 25723
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
intraspecies homolog to VASH1 (>50 p100)
Homologene
FAMILY
CATEGORY regulatory
SUBCELLULAR LOCALIZATION
basic FUNCTION
  • exhibited antiangiogenic activity
  • implicated in negative regulatory system of angiogenesis genetically programmed in endothelial cells
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • in combination with vasohibin-1, forms a novel family of angiogenesis inhibitors
  • cell & other
    REGULATION
    induced by the stimulation with VEGF or FGF2, and selectively affects on endothelial cells and inhibits angiogenesis
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS