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FLASH GENE
Symbol SLC22A24 contributors: mct - updated : 07-01-2021
HGNC name solute carrier family 22, member 24
HGNC id 28542
Location 11q12.3      Physical location : 62.847.413 - 62.911.693
Synonym symbol(s) MGC34821, NET46
DNA
TYPE functioning gene
STRUCTURE 64.28 kb     4 Exon(s)
MAPPING cloned Y linked N status provisional
RNA
TRANSCRIPTS type messenger
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
4 - 1663 - 322 - 2019 31553721
10 - 2101 - 552 - 2019 31553721
EXPRESSION
Type
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestiveliver   lowly Homo sapiens
Urinarykidneytubuleconvoluted tubule highly Homo sapiens
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
HOMOLOGY
Homologene
FAMILY
  • solute carrier family 22 (SLC22) facilitator superfamily
  • CATEGORY transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • organic anion transport
  • SLC22A24 has likely a specialized role in the kidney and appears to function in the reabsorption of organic anions, and in particular, anionic steroids
  • OATS4 (SLC22A9, SLC22A10, SLC2A24, and SLC22A25) members are specifically associated with conjugated sex hormones
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s)
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    SystemTypeDisorderPubmed
    miscelleaneous  
    possibilities for SLC22A24 as a pharmacological target for regulating steroid levels
    ANIMAL & CELL MODELS