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FLASH GENE
Symbol ZNF569 contributors: - updated : 19-09-2007
HGNC name zinc finger protein 569
HGNC id 24737
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • eighteen C2H2-type zinc-finger
  • a KRAB domain
    • HOMOLOGY
    interspecies homolog to rattus Zfp74 (85.29 pc)
    homolog to chimpanzee ZFP569 (100.00 pc)
    homolog to murine Zfp74 (84.09 pc)
    Homologene
    FAMILY krueppel C2H2-type zinc-finger protein family
    CATEGORY regulatory
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus,chromatin/chromosome
    basic FUNCTION
  • acting as a transcriptional repressor, suppressing MAPK signaling pathway
    • CELLULAR PROCESS nucleotide, transcription, regulation
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA binding
    RNA
    small molecule metal binding,
  • Zn2+
    • protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS