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FLASH GENE

Symbol

ZNF569

contributors: - updated : 19-09-2007

HGNC name	zinc finger protein 569
HGNC id	24737

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

EXPRESSION

Type	restricted

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive mouth       moderately Endocrine neuroendocrine pituitary     highly Lymphoid/Immune thymus       moderately Nervous brain       moderately Reproductive male system testis     moderately Respiratory respiratory tract trachea     moderately

cell lineage

cell lines

fluid/secretion

at STAGE

physiological period

embryo, fetal, pregnancy

Text	embryonic tissue

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	eighteen C2H2-type zinc-finger
	a KRAB domain

HOMOLOGY

interspecies	homolog to rattus Zfp74 (85.29 pc)
	homolog to chimpanzee ZFP569 (100.00 pc)
	homolog to murine Zfp74 (84.09 pc)

Homologene

FAMILY

krueppel C2H2-type zinc-finger protein family

CATEGORY

regulatory

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION

acting as a transcriptional repressor, suppressing MAPK signaling pathway

CELLULAR PROCESS

nucleotide, transcription, regulation

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS