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FLASH GENE

Symbol

TMEM30B

contributors: mct - updated : 17-01-2015

HGNC name	transmembrane protein 30B
HGNC id	27254

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

two-transmembrane- doamins

HOMOLOGY

Homologene

FAMILY

CATEGORY

unknown/unspecified

SUBCELLULAR LOCALIZATION

plasma membrane

basic FUNCTION

components of phospholipid-translocators

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein	interactions of TMEM30A and TMEM30B with multiple members of the human P(4)-ATPase family, suggesting that these proteins perform broader functions in human physiology than thus far assumed
	ATP8B1 shifted from the endoplasmic reticulum (ER) to the plasma membrane upon coexpression of TMEM30A or TMEM30B
	TMEM30 is not essential for the ER exit or TGN localization of ATP9B, whereas TMEMA, but not TMEM30B, is required for ER exit and/or recycling endosomal localization of ATP11B

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS