Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

SLC25A43

contributors: mct - updated : 06-11-2020

HGNC name	solute carrier family 25, member 43
HGNC id	30557

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

DNA

TYPE	functioning gene
STRUCTURE	55.15 kb     5 Exon(s)

MAPPING

cloned

Y

linked

N

status

provisional

RNA

TRANSCRIPTS	type	messenger

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed NM_145305 5 - 2507 NP_660348 - 341 - 2016 26721434

EXPRESSION

Type

widely

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Digestive intestine small intestine     highly   stomach       highly Nervous brain hindbrain cerebellum   highly   brain forebrain cerebral cortex   highly Olfactory (smell) olfactory bulb       highly Reproductive female system uterus cervix   highly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains

three solcar repeats

HOMOLOGY

interspecies

ortholog to murine Slc25a43 (86 pc)

Homologene

FAMILY

mitochondrial carrier family

CATEGORY

transport carrier

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,cytoplasm,organelle,mitochondria,inner
	intracellular,cytoplasm,organelle,membrane

basic FUNCTION	required for the accumulation of coenzyme a in the mitochondrial matrix
	epigenetic changes in SLC25A43 gene could likely be of importance in breast carcinogenesis
	role for SLC25A43 as a regulator of cell cycle progression and proliferation through a putative mitochondrial checkpoint
	SLC25A43 expression is altered at the gene and protein levels in basal cell carcinoma

CELLULAR PROCESS

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

RNA

small molecule

protein

cell & other

REGULATION

ASSOCIATED DISORDERS

corresponding disease(s)

HARTS

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   in basal cell carcinoma compared with healthy skin

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS